Are you sure ... Natives and their size / goverment are necessary to balance the game. Removing them is dangerous. I assume its for a better fitting to your roleplay background.
No Natives means that Fed and Lizzard gets an extra kick off bonus, because they earn more MC from their colonists.
No Natives means that most ships are equiped mit non Transwarps ... that gives the Colonies and Lizzards a bonus .... scooping and mining fuel for overpowered drives are key.
Low money leads to more bases than builds - means we hit the limit very late (nobody get PPs because original queue is used).
Birds and Fascists would be the most dificult races to play ... they need all tech levels on a higher level to compete. Fed has Superrefit and Colonies / Rebels have the best firepower per ship ratio.
You can compensate no natives with a bigger bunch of colonists and more money at the start ... or introduce natives with a lower percentage ... wind fall profits from minor developed peoples in the galaxy :)
Show Media Item - Oh ... >> 0% Native Probability Are you sure ... Natives...